Instrumental variables for implementation science: exploring context-dependent causal pathways between implementation strategies and evidence-based interventions.

ABSTRACT:

Background

The impact of both implementation strategies (IS) and evidence-based interventions (EBI) can vary across contexts, and a better understanding of how and why this occurs presents fundamental but challenging questions that implementation science as a field will need to grapple with. We use causal epidemiologic methods to explore the mechanisms of why sharp distinctions between implementation strategies (IS) and efficacy of an evidence-based intervention (EBI) may fail to recognize that the effect of an EBI can be deeply intertwined and dependent on the context of the IS leading to its uptake.

Methods

We explore the use of instrumental variable (IV) analyses as a critical tool for implementation science methods to isolate three relevant quantities within the same int

SUBMITTER: Mody A 

PROVIDER: S-EPMC10731809 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature