Phenylpropanoid-enriched broccoli seedling extract can reduce inflammatory markers and pain behavior.

ABSTRACT:

Background

Pain is a worldwide problem requiring an effective, affordable, non-addictive therapy. Using the edible plant broccoli, a growth protocol was developed to induce a concentrated combinatorial of potential anti-inflammatories in seedlings.

Methods

A growth method was utilized to produce a phenylpropanoid-rich broccoli sprout extract, referred to as Original Extract (OE). OE was concentrated and then resuspended for study of the effects on inflammation events. A rabbit disc model of inflammation and degeneration, and, a mouse model of pain behavior were used for in vivo and in vitro tests. To address aspects of mammalian metabolic processing, the OE was treated with the S9 liver microsome fraction derived from mouse, for use in a mouse in vivo study. Analytical chemi

SUBMITTER: Gurgul AA 

PROVIDER: S-EPMC10731810 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature