Risk stratification in patients with structurally normal hearts: Does fibrosis type matter?

ABSTRACT:

Objectives

The study sought to assess the prognostic significance of nonischemic myocardial fibrosis (MF) on cardiovascular magnetic resonance (CMR)-both macroscopic MF assessed by late gadolinium enhancement (LGE) and diffuse microscopic MF quantified by extracellular volume fraction (ECV)-in patients with structurally normal hearts.

Background

The clinical relevance of tissue abnormalities identified by CMR in patients with structurally normal hearts remains unclear.

Methods

Consecutive patients undergoing CMR were screened for inclusion to identify those with LGE imaging and structurally normal hearts. ECV was calculated in patients with available T1 mapping. The associations between myocardial fibrosis and the outcomes of all-cause mortality, new-onset heart failu

SUBMITTER: Gil KE 

PROVIDER: S-EPMC10732365 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature