Ontology highlight
ABSTRACT:
SUBMITTER: Mao W
PROVIDER: S-EPMC10732598 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Mao Weiting W Wang Zhichao Z Wen Siting S Lin Yan Y Gu Jiayun J Sun Ju J Wang Huan H Cao Qi Q Xu Yindi Y Xu Xiaojuan X Cai Xuwang X
Virulence 20231129 1
<i>Glaesserella parasuis</i> is an early colonizer of the swine upper respiratory tract and can break through the respiratory barrier for further invasion. However, the mechanisms underlying <i>G. parasuis</i> increases epithelial barrier permeability remain unclear. This study demonstrates that <i>G. parasuis</i> cytolethal distending toxin (CDT) induces p53-dependent apoptosis in new-born piglet tracheal (NPTr) cells. Moreover, we report for the first time that leucine-rich repeat-containing p ...[more]