An assessment of the ECETOC TRA Consumer tool performance as a screening level tool.

ABSTRACT:

Background

The European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) Targeted Risk Assessment (TRA) Consumer tool was developed to fill in a methodology gap for a high throughput, screening level tool to support industry compliance with the European Union's Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) regulation.

Objective

To evaluate if the TRA Consumer tool has met its design of being a screening level tool (i.e., one which does not under-predict potential exposures).

Methods

The TRA Consumer tool algorithms and defaults were reviewed and performance benchmarked vs. other consumer models and/or empirical data. Findings from existing reviews of the TRA consumer tool were also considered and addressed.

Results

T

SUBMITTER: Zaleski RT 

PROVIDER: S-EPMC10733139 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature