Sleep dysfunction associated with worse chemotherapy-induced peripheral neurotoxicity functional outcomes.

ABSTRACT:

Purpose

Sleep problems are commonly reported by cancer survivors; however, knowledge of the impact of chemotherapy-induced peripheral neurotoxicity (CIPN) on sleep quality remains limited. In this study, we explored the impact of CIPN on sleep quality, as well as identified clinical characteristics associated with poor sleep quality.

Methods

Participants were assessed cross-sectionally post-neurotoxic chemotherapy. CIPN severity was graded using a range of questionnaires that assessed CIPN severity and quality of life, as well as neurological grading scales. Sleep quality was assessed using a self-rated questionnaire (Pittsburgh Sleep Quality Index, PSQI). Participants with poor sleep quality were further grouped according to whether sleep impairment was due to CIPN or other

SUBMITTER: Mahfouz FM 

PROVIDER: S-EPMC10733204 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature