Pendelluft in hypoxemic patients resuming spontaneous breathing: proportional modes versus pressure support ventilation.

ABSTRACT:

Background

Internal redistribution of gas, referred to as pendelluft, is a new potential mechanism of effort-dependent lung injury. Neurally-adjusted ventilatory assist (NAVA) and proportional assist ventilation (PAV +) follow the patient's respiratory effort and improve synchrony compared with pressure support ventilation (PSV). Whether these modes could prevent the development of pendelluft compared with PSV is unknown. We aimed to compare pendelluft magnitude during PAV + and NAVA versus PSV in patients with resolving acute respiratory distress syndrome (ARDS).

Methods

Patients received either NAVA, PAV + , or PSV in a crossover trial for 20-min using comparable assistance levels after controlled ventilation (> 72 h). We assessed pendelluft (the percentage of lost volume

SUBMITTER: Arellano DH 

PROVIDER: S-EPMC10733241 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature