Incidence density of hyperuricemia and association between metabolism-related predisposing risk factors and serum urate in Chinese adults: a cohort study.

ABSTRACT:

Background

Evidence regarding the association between metabolism-related indicators and serum urate (SU) is limited. We aimed to obtain the incidence density of hyperuricemia and to explore the association between metabolism-related predisposing risk factors and SU.

Methods

A total of 48,979 Chinese adults from the Beijing Physical Examination Center were included in the study. The partial least squares path model was used to explore the relationship between SU and metabolism-related risk factors. The generalized additive model was used for smooth curve fitting, showing the sex-specific associations of SU at follow-up with baseline fasting blood glucose (FBG) concentrations and age.

Results

The incidence density of hyperuricemia was 78/1000 person-years. Baseline SU,

SUBMITTER: Liang H 

PROVIDER: S-EPMC10733531 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature