Impaired proactive cognitive control in Parkinson's disease.

ABSTRACT: Adaptive control has been studied in Parkinson's disease mainly in the context of proactive control and with mixed results. We compared reactive- and proactive control in 30 participants with Parkinson's disease to 30 age matched healthy control participants. The electroencephalographic activity of the participants was recorded over 128 channels while they performed a numerical Stroop task, in which we controlled for confounding stimulus-response learning. We assessed effects of reactive- and proactive control on reaction time-, accuracy- and electroencephalographic time-frequency data. Behavioural results show distinct impairments of proactive- and reactive control in participants with Parkinson's disease, when tested on their usual medication. Compared to healthy control participants, pa

SUBMITTER: Kricheldorff J 

PROVIDER: S-EPMC10733811 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature