REtinal Detachment Outcomes Study (REDOS): study protocol for a factorial, randomized controlled trial.

ABSTRACT:

Background

Few large randomized controlled trials provide strong evidence to guide surgical repair of primary rhegmatogenous retinal detachment (RRD) repair. The purpose of this factorial, single-blind, randomized controlled trial is to analyze and compare the surgical outcomes, functional visual outcomes, complications, and quality of life associated with RRD repair using (A) pars plana vitrectomy only (PPV) or PPV with scleral buckle (PPV-SB) and (B) sulfur hexafluoride gas (SF₆) or perfluoropropane gas (C₃F₈) tamponade.

Methods

Eligible patients with moderately complex RRD will be randomized 1:1 to PPV or PPV-SB and 1:1 to SF₆ or C₃F₈ gas tamponade. Approximately 560 patients will be recruited to be able to

SUBMITTER: Hebert M 

PROVIDER: S-EPMC10734075 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature