Efficacy and safety of glucocorticoids use in patients with COVID-19: a systematic review and network meta‑analysis.

ABSTRACT:

Background

Currently, some meta-analyses on COVID-19 have suggested that glucocorticoids use can reduce the mortality rate of COVID-19 patients, utilization rate of invasive ventilation, and improve the prognosis of patients. However, optimal regimen and dosages of glucocorticoid remain unclear. Therefore, the purpose of this network meta-analysis is to analyze the efficacy and safety of glucocorticoids in treating COVID-19 at regimens.

Methods

This meta-analysis retrieved randomized controlled trials from the earliest records to December 30, 2022, published in PubMed, Embase, Cochrane Library, CNKI Database and Wanfang Database, which compared glucocorticoids with placebos for their efficacy and safety in the treatment of COVID-19, Effects of different treatment regimens, t

SUBMITTER: He Q 

PROVIDER: S-EPMC10734118 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature