Dataset Information
Genetic dissection of the degradation pathways for the mycotoxin fusaric acid in Burkholderia ambifaria T16.
Ontology highlight
ABSTRACT: Importance
Fusaric acid (FA) is an important virulence factor produced by several Fusarium species. These fungi are responsible for wilt and rot diseases in a diverse range of crops. FA is toxic for animals, humans and soil-borne microorganisms. This mycotoxin reduces the survival and competition abilities of bacterial species able to antagonize Fusarium spp., due to its negative effects on viability and the production of antibiotics effective against these fungi. FA biodegradation is not a common characteristic among bacteria, and the determinants of FA catabolism have not been identified so far in any microorganism. In this study, we identified genes, enzymes, and metabolic pathways involved in the degradation of FA in the soil bacterium Burkholderia ambifaria T16. Our results provide insights into the catabolism of a pyridine-derivative involved in plant pathogenesis by a rhizosphere bacterium.
SUBMITTER: Vinacour M
PROVIDER: S-EPMC10734416 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Publications
Genetic dissection of the degradation pathways for the mycotoxin fusaric acid in <i>Burkholderia ambifaria</i> T16.
Applied and environmental microbiology 20231206 12
<h4>Importance</h4>Fusaric acid (FA) is an important virulence factor produced by several <i>Fusarium</i> species. These fungi are responsible for wilt and rot diseases in a diverse range of crops. FA is toxic for animals, humans and soil-borne microorganisms. This mycotoxin reduces the survival and competition abilities of bacterial species able to antagonize <i>Fusarium</i> spp., due to its negative effects on viability and the production of antibiotics effective against these fungi. FA biodeg ...[more]
