Trends in Incidence of Carbapenem-Resistant Enterobacterales in 7 US Sites, 2016─2020.

ABSTRACT:

Background

We described changes in 2016─2020 carbapenem-resistant Enterobacterales (CRE) incidence rates in 7 US sites that conduct population-based CRE surveillance.

Methods

An incident CRE case was defined as the first isolation of Escherichia coli, Klebsiella spp., or Enterobacter spp. resistant to ≥1 carbapenem from a sterile site or urine in a surveillance area resident in a 30-day period. We reviewed medical records and classified cases as hospital-onset (HO), healthcare-associated community-onset (HACO), or community-associated (CA) CRE based on healthcare exposures and location of disease onset. We calculated incidence rates using census data. We used Poisson mixed effects regression models to perform 2016─2020 trend analyses, adjusting for sex,

SUBMITTER: Duffy N 

PROVIDER: S-EPMC10734676 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature