Bibliometric analysis of global research trends in adeno-associated virus vector for gene therapy (1991-2022).

ABSTRACT:

Background

Gene therapy involves introducing and editing foreign genes in the body to treat and prevent genetic diseases. Adeno-associated virus (AAV) vector has become a widely used tool in gene therapy due to its high safety and transfection efficiency.

Methods

This study employs bibliometric analysis to explore the foundation and current state of AAV vector application in gene therapy research. A total of 6,069 publications from 1991 to 2022 were analyzed, retrieved from the Science Citation Index Expanded (SCI-E) within the Web of Science Core Collection (WoSCC) of Clarivate Analytics. Institutions, authors, journals, references, and keywords were analyzed and visualized by using VOSviewer and CiteSpace. The R language and Microsoft Excel 365 were used for statistical an

SUBMITTER: Jiang F 

PROVIDER: S-EPMC10739348 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature