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IntelliGenes: a novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles.


ABSTRACT:

Summary

In this article, we present IntelliGenes, a novel machine learning (ML) pipeline for the multi-genomics exploration to discover biomarkers significant in disease prediction with high accuracy. IntelliGenes is based on a novel approach, which consists of nexus of conventional statistical techniques and cutting-edge ML algorithms using multi-genomic, clinical, and demographic data. IntelliGenes introduces a new metric, i.e. Intelligent Gene (I-Gene) score to measure the importance of individual biomarkers for prediction of complex traits. I-Gene scores can be utilized to generate I-Gene profiles of individuals to comprehend the intricacies of ML used in disease prediction. IntelliGenes is user-friendly, portable, and a cross-platform application, compatible with Microsoft Win

SUBMITTER: DeGroat W 

PROVIDER: S-EPMC10739559 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature