The effect of general anesthesia and conscious sedation in endovascular thrombectomy for acute ischemic stroke: an updated meta-analysis of randomized controlled trials and trial sequential analysis.

ABSTRACT:

Objectives

General anesthesia (GA) and conscious sedation (CS) are common methods for endovascular thrombectomy (EVT) in acute ischemic stroke (AIS). However, the risks and benefits of each strategy are unclear. This study aimed to summarize the latest RCTs and compare the postoperative effects of the two methods on EVT patients.

Materials and methods

We systematically searched the database for GA and CS in AIS patients during EVT. The retrieval time was from the creation of the database until March 2023. The quality of the studies was evaluated using the Cochrane risk of bias tool. Random-effects or fixed-effects meta-analyses were used to assess all outcomes.

Results

We preliminarily identified 304 studies, of which 8 were included. Based on the pooled estimates, th

SUBMITTER: Peng Z 

PROVIDER: S-EPMC10740157 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature