Interleaved configurations of percutaneous epidural stimulation enhanced overground stepping in a person with chronic paraplegia.

ABSTRACT: Descending motor signals are disrupted after complete spinal cord injury (SCI) resulting in loss of standing and walking. We previously restored standing and trunk control in a person with a T3 complete SCI following implantation of percutaneous spinal cord epidural stimulation (SCES). We, hereby, present a step-by-step procedure on configuring the SCES leads to initiate rhythmic lower limb activation (rhythmic-SCES) resulting in independent overground stepping in parallel bars and using a standard walker. Initially, SCES was examined in supine lying at 2 Hz before initiating stepping-like activity in parallel bars using 20 or 30 Hz; however, single lead configuration (+2, -5) resulted in lower limb adduction and crossing of limbs, impairing the initiation of overground stepping. After 6 m

SUBMITTER: Gorgey AS 

PROVIDER: S-EPMC10740173 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature