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An extranodal Richter's syndrome presenting with cardiac diffuse large B-cell lymphoma: a case report.


ABSTRACT:

Background

Richter's syndrome (RS) defines the transformation of chronic lymphocytic leukemia into high-grade lymphoma, which usually involves lymph nodes and bone marrow. Extranodal involvement of the heart is an extremely rare condition. Patients with heart involvement tended to have a low response to chemotherapy and relative poor prognosis. The transformation process of RS is often insidious and nonspecific making it challenging to diagnose.

Case presentation

A 64-year-old woman wih a history of chronic lymphocytic leukemia (CLL) presented with intermittent chest pain and was diagnosed with non-ST-elevation myocardial infarction (NSTEMI). However, the contrast enhanced echocardiography revealed a large irregular mass, measuring about 75.4 mm × 37.5 mm, located on the lat

SUBMITTER: Wang H 

PROVIDER: S-EPMC10740268 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature