Interaction between Gut Microbiota and Dendritic Cells in Colorectal Cancer.

ABSTRACT: Colorectal cancer (CRC) is a malignancy that manifests in serial stages and has been observed to have an escalating incidence in modern societies, causing a significant global health problem. The development of CRC is influenced by various exogenous factors, including lifestyle, diet, nutrition, environment, and microbiota, that can affect host cells, including immune cells. Various immune dysfunctions have been recognized in patients with CRC at different stages of this disease. The signature of microbiota in the development of CRC-inflammation related to obesity, diet, and reactive host cells, such as dendritic cells (DCs)-has been highlighted by many studies. This study focuses on DCs, the primary cellular mediators linking innate and adaptive immune responses against cancer. In additio

SUBMITTER: Zaher K 

PROVIDER: S-EPMC10741039 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature