Association Between Menopausal Hormone Therapy and Risk for Parkinson's Disease.

ABSTRACT:

Background

The relationship between menopausal hormone therapy (MHT) and risk of Parkinson's disease (PD) remains controversial.

Objective

This nationwide population-based cohort study investigated the association between MHT and PD development.

Methods

Data from the National Health Insurance System of South Korea from 2007 to 2020 were used. The MHT group included women who underwent MHT for the first time between 2011-2014, while the non-MHT group included women who visited a healthcare provider for menopause during the same period but never received hormonal therapy. We used propensity score matching (1 : 1) to adjust for potential confounders, and Cox regression models to assess the association between MHT and PD.

Results

We selected 303,260 female particip

SUBMITTER: Yuk JS 

PROVIDER: S-EPMC10741322 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature