Reelin Signaling and Synaptic Plasticity in Schizophrenia.

ABSTRACT: Recent research emphasizes the significance of studying the quality of life of schizophrenia patients, considering the complex nature of the illness. Identifying neuronal markers for early diagnosis and treatment is crucial. Reelin (RELN) stands out among these markers, with genetic studies highlighting its role in mental health. Suppression of RELN expression may contribute to cognitive deficits by limiting dendritic proliferation, affecting neurogenesis, and leading to improper neuronal circuits. Although the physiological function of reelin is not fully understood, it plays a vital role in hippocampal cell stratification and neuroglia formation. This analysis explores reelin's importance in the nervous system, shedding light on its impact on mental disorders such as schizophrenia, pavin

SUBMITTER: Markiewicz R 

PROVIDER: S-EPMC10741648 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature