The Complex Role of the Microbiome in Non-Small Cell Lung Cancer Development and Progression.

ABSTRACT: In recent years, there has been a growing interest in the relationship between microorganisms in the surrounding environment and cancer cells. While the tumor microenvironment predominantly comprises cancer cells, stromal cells, and immune cells, emerging research highlights the significant contributions of microbial cells to tumor development and progression. Although the impact of the gut microbiome on treatment response in lung cancer is well established, recent investigations indicate complex roles of lung microbiota in lung cancer. This article focuses on recent findings on the human lung microbiome and its impacts in cancer development and progression. We delve into the characteristics of the lung microbiome and its influence on lung cancer development. Additionally, we explore the c

SUBMITTER: Souza VGP 

PROVIDER: S-EPMC10741843 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature