Inter-Rater Variability of Prostate Lesion Segmentation on Multiparametric Prostate MRI.

ABSTRACT:

Introduction

External radiotherapy is a major treatment for localized prostate cancer (PCa). Dose escalation to the whole prostate gland increases biochemical relapse-free survival but also acute and late toxicities. Dose escalation to the dominant index lesion (DIL) only is of growing interest. It requires a robust delineation of the DIL. In this context, we aimed to evaluate the inter-observer variability of DIL delineation.

Material and methods

Two junior radiologists and a senior radiation oncologist delineated DILs on 64 mpMRIs of patients with histologically confirmed PCa. For each mpMRI and each reader, eight individual DIL segmentations were delineated. These delineations were blindly performed from one another and resulted from the individual analysis of the T2, app

SUBMITTER: Jeganathan T 

PROVIDER: S-EPMC10741937 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature