Characterization of Cortical and Subcortical Structural Brain Asymmetry in Adults with and without Dyslexia.

ABSTRACT: Multiple cortical (planum temporale, supramarginal gyrus, fusiform gyrus) and subcortical (caudate, putamen, and thalamus) regions have shown different functional lateralization patterns for skilled vs. dyslexic readers. The extent to which skilled and dyslexic adult readers show differential structural lateralization remains to be seen. Method: Participants included 72 adults (N = 41 skilled; N = 31 dyslexic) who underwent a high-resolution MRI brain scan. The grey matter volume of the cortical and subcortical structures was extracted. Results: While there were clear behavioral differences between the groups, there were no differences in any of the isolated structures (i.e., either total size or asymmetry index) and limited evidence for any brain-behavior relationships. We did find a sign

SUBMITTER: Cummine J 

PROVIDER: S-EPMC10741947 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature