Functions of RNA-Binding Proteins in Cardiovascular Disease.
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ABSTRACT:
SUBMITTER: Ruffenach G
PROVIDER: S-EPMC10742114 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
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Functions of RNA-Binding Proteins in Cardiovascular Disease.
Ruffenach Grégoire G Medzikovic Lejla L Sun Wasila W Hong Jason J Eghbali Mansoureh M
Cells 20231208 24
Gene expression is under tight regulation from the chromatin structure that regulates gene accessibility by the transcription machinery to protein degradation. At the transcript level, this regulation falls on RNA-binding proteins (RBPs). RBPs are a large and diverse class of proteins involved in all aspects of a transcript's lifecycle: splicing and maturation, localization, stability, and translation. In the past few years, our understanding of the role of RBPs in cardiovascular diseases has ex ...[more]
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