Evaluation of a Novel Fixative Solution for Liquid-Based Cytology in Diagnostic Cytopathology.

ABSTRACT: Since its introduction in the early 2000s, liquid-based cytology (LBC) has been increasingly used for gynecologic and non-gynecologic cytology, and its multiple advantages have been widely recognized. The aim of this study was to investigate the use of a new fixative and pre-analytical method for morphological diagnosis in cytological samples. In particular, we evaluated the effect of a novel preservative solution on the preparation of diagnostic slides by comparing it with the standard reference used globally in cytology laboratories. This study included both gynecological (n = 139) and non-gynecological (n = 183) samples. Several morphologic variables were then identified and evaluated. Using this approach, we were then able to demonstrate the suitability of the new system,

SUBMITTER: Casatta N 

PROVIDER: S-EPMC10742394 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature