Effects of Radioactive ⁵⁶MnO₂ Particle Inhalation on Mouse Lungs: A Comparison between C57BL and BALB/c.

ABSTRACT: The effects of residual radiation from atomic bombs have been considered to be minimal because of its low levels of external radioactivity. However, studies involving atomic bomb survivors exposed to only residual radiation in Hiroshima and Nagasaki have indicated possible adverse health effects. Thus, we investigated the biological effects of radioactive dust of manganese dioxide 56 (⁵⁶MnO₂), a major radioisotope formed in soil by neutron beams from a bomb. Previously, we investigated C57BL mice exposed to ⁵⁶MnO₂ and found pulmonary gene expression changes despite low radiation doses. In this study, we examined the effects in a radiation-sensitive strain of mice, BALB/c, and compared them with those in C57BL mice. The animals were exposed to

SUBMITTER: Abishev Z 

PROVIDER: S-EPMC10743477 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature