Drosophila melanogaster Transcriptome Response to Different Wolbachia Strains.

ABSTRACT: Wolbachia is a maternally inherited, intercellular bacterial symbiont of insects and some other invertebrates. Here, we investigated the effect of two different Wolbachia strains, differing in a large chromosomal inversion, on the differential expression of genes in D. melanogaster females. We revealed significant changes in the transcriptome of the infected flies compared to the uninfected ones, as well as in the transcriptome of flies infected with the Wolbachia strain, wMelPlus, compared to flies infected with the wMelCS¹¹² strain. We linked differentially expressed genes (DEGs) from two pairwise comparisons, "uninfected-wMelPlus-infected" and "uninfected-wMelCS¹¹²-infected", into two gene networks, in which the following functional grou

SUBMITTER: Gruntenko NE 

PROVIDER: S-EPMC10743526 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature