Supramolecular Nature of Multicomponent Crystals Formed from 2,2'-Thiodiacetic Acid with 2,6-Diaminopurine or N9-(2-Hydroxyethyl)adenine.

ABSTRACT: The synthesis and characterization of the multicomponent crystals formed by 2,2'-thiodiacetic acid (H₂tda) and 2,6-diaminopurine (Hdap) or N9-(2-hydroxyethyl)adenine (9heade) are detailed in this report. These crystals exist in a salt rather than a co-crystal form, as confirmed by single crystal X-ray diffractometry, which reflects their ionic nature. This analysis confirmed proton transfer from the 2,2'-thiodiacetic acid to the basic groups of the coformers. The new multicomponent crystals have molecular formulas [(H9heade⁺)(Htda^-)] 1 and [(H₂dap⁺)₂(tda^2-)]·2H₂O 2. These were also characterized using FTIR, ¹H and ¹³C NMR and mass spectroscopies, elemental analysis, a

SUBMITTER: Belmont-Sanchez JC 

PROVIDER: S-EPMC10743529 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature