Meta-analysis of cortical thickness reduction in adult schizophrenia.

ABSTRACT:

Background

Numerous neuroimaging studies using surface-based morphometry analyses have reported altered cortical thickness among patients with schizophrenia, but the results have been inconsistent. We sought to provide a whole-brain meta-analysis, which may help enhance the spatial accuracy of identification.

Methods

We conducted a meta-analysis of whole-brain studies that explored cortical thickness alteration among adult patients with schizophrenia, including first-episode patients with schizophrenia, and patients with chronic schizophrenia, compared with healthy controls by using the seed-based d mapping with permutation of subject images (SDM-PSI) software.

Results

A systematic literature search identified 25 studies (33 data sets) of cortical thickness, including

SUBMITTER: Sun S 

PROVIDER: S-EPMC10743639 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature