The Plasma Membrane H⁺ ATPase CsPMA2 Regulates Lipid Droplet Formation, Appressorial Development and Virulence in Colletotrichum siamense.

ABSTRACT: Plasma membrane H⁺-ATPases (PMAs) play an important role in the pathogenicity of pathogenic fungi. Lipid droplets are important storage sites for neutral lipids in fungal conidia and hyphae and can be used by plant pathogenic fungi for infection. However, the relationship between plasma membrane H⁺-ATPase, lipid droplets and virulence remains unclear. Here, we characterized a plasma membrane H⁺-ATPase, CsPMA2, that plays a key role in lipid droplet formation, appresorial development and virulence in C. siamense. Deletion of CsPMA2 impaired C. siamense conidial size, conidial germination, appressorial development and virulence but did not affect hyphal growth. ΔCsPMA2 increased the sensitivity of C. siamense to phytic acid

SUBMITTER: Liu Y 

PROVIDER: S-EPMC10743824 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature