Ontology highlight
ABSTRACT:
SUBMITTER: Singh AY
PROVIDER: S-EPMC10744544 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Singh Angad Yuvraj AY Jain Sanjay S
Life (Basel, Switzerland) 20231212 12
We present a simple mathematical model that captures the evolutionary capabilities of a prebiotic compartment or protocell. In the model, the protocell contains an autocatalytic set whose chemical dynamics is coupled to the growth-division dynamics of the compartment. Bistability in the dynamics of the autocatalytic set results in a protocell that can exist with two distinct growth rates. Stochasticity in chemical reactions plays the role of mutations and causes transitions from one growth regim ...[more]