Low Urinary Free Cortisol as a Risk Factor for Patients with Variceal Bleeding.

ABSTRACT: Background and Objectives: Specificity and reliability issues of the current cortisol assessment methods lead to limitations on the accurate assessment of relative adrenal insufficiency. Although free cortisol provides a more accurate evaluation of adrenal cortisol production, the expense and time-consuming nature of these assays make them impractical for routine use. Research has, thus, focused on alternative methods, such as indirectly measuring free cortisol using Coolens' equation or directly assessing salivary cortisol concentration, which is considered a more favorable approach despite associated challenges like sampling issues and infection risks. The aim of this study was to explore correlations between 24 h urinary free cortisol (UFC), free plasma cortisol, serum total cort

SUBMITTER: Aggeletopoulou I 

PROVIDER: S-EPMC10744924 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature