The impact of SARS-CoV-2 infection on renal function in patients with biopsy-proven kidney diseases.

ABSTRACT:

Background

We sought to evaluate the long-term effects of COVID-19 on renal function in patients with biopsy-proven kidney diseases.

Methods

A total of 451 patients with biopsy-proven kidney disease and at least 12 months of follow-up subsequent to COVID-19 pandemic onset were included in the study. The primary study endpoint was a composite of a persistent decline of more than 30% in eGFR or ESRD.

Results

23.1% of patients had COVID-19 during a follow-up period of 2.5 y (0.8-2.6), while 17.6% of patients reached the composite endpoint. Those with COVID-19 were more likely to reach the composite endpoint [26.7% vs. 14.8%; OR, 2.1 (95%CI, 1.23-3.58), p = 0.006). There was a significant eGFR change in the first year of follow-up between the two study groups [-2.24 (95%C

SUBMITTER: Obrisca B 

PROVIDER: S-EPMC10745175 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature