Comparative Genomic Analysis of Cutibacterium spp. Isolates in Implant-Associated Infections.

ABSTRACT: Bacteria of the genus Cutibacterium are Gram-positive commensals and opportunistic pathogens that represent a major challenge in the diagnosis and treatment of implant-associated infections (IAIs). This study provides insight into the distribution of different sequence types (STs) of C. acnes, and the presence of virulence factors (VFs) in 64 Cutibacterium spp. isolates from suspected or confirmed IAIs obtained during routine microbiological diagnostics. Fifty-three C. acnes, six C. avidum, four C. granulosum, and one C. namnetense isolate, collected from different anatomical sites, were included in our study. Using whole-genome sequencing and a single-locus sequencing typing scheme, we successfully characterized all C. acnes strains

SUBMITTER: Erbeznik A 

PROVIDER: S-EPMC10745319 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature