The Second Derivative of Fullerene C₆₀ (SD-C₆₀) and Biomolecular Machinery of Hydrogen Bonds: Water-Based Nanomedicine.

ABSTRACT: The human body contains 60-70% water, depending on age. As a body fluid, it is not only a medium in which physical and chemical processes take place, but it is also one of the active mediators. Water is the richest substance with non-covalent hydrogen bonds. Water molecules, by themselves (in vacuum), are diamagnetic but when organized into clusters, they become diamagnetic or paramagnetic. Also, biomolecules (DNA, collagen, clathrin, and other proteins) have non-covalent hydrogen bonds in their structure. The interaction, as well as signal transmission, between water and biomolecules is achieved through the vibrations of covalent and non-covalent hydrogen bonds, which determine the state and dynamics of conformational changes in biomolecules. Disruptive conformational changes in biomolecu

SUBMITTER: Matija LR 

PROVIDER: S-EPMC10745578 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature