Three-dimensional thermophotonic super-resolution imaging by spatiotemporal diffusion reversal method.

ABSTRACT: Spatial super-resolution in thermophotonic imaging was achieved using a combination of spatial second-derivative forming, spatial gradient adaptive filtering, and Richardson-Lucy deconvolution in conjunction with the construction of an experimental point spread function. When implemented through enhanced truncation-correlation photothermal coherence tomography (eTC-PCT), it was possible to restore blurred infrared thermophotonic images to their prediffusion optical resolution state. This modality was tested in various biological applications and proved to be capable of imaging fine axial cracks in human teeth, well-patterned anatomical subsurface structures of a mouse brain, and neovascularization in a mouse thigh due to the rapid proliferation of cancer cells. This modality was found to b

SUBMITTER: Thapa D 

PROVIDER: S-EPMC10745684 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature