In silico screening of herbal phytochemicals to develop a Rasayana for immunity against Nipah virus.

ABSTRACT:

Background

The first emergence of the Nipah virus (NiV) in 1998 from Malaysia became a major concern when it came to light and resurfaced on different occasions thereafter. NiV is a bat-borne zoonotic and pleomorphic virus that causes severe infection in human and animal hosts. Studies revealed fruit bats are the major reservoirs as natural hosts and pigs as intermediate hosts for the spread of this infection. This became a major concern as the disease was characterized by high pathogenicity varying from 40% to 80% depending on its acuteness. Moreover, the solemnity lies in the fact that the infection transcends from being a mere mild illness to an acute respiratory infection leading to fatal encephalitis with a reportedly high mortality rate. Currently, there is no treatment or va

SUBMITTER: Debroy B 

PROVIDER: S-EPMC10746367 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature