Amino acid-based enteral nutrition is effective for pediatric Crohn's disease: a multicenter prospective study.

ABSTRACT:

Background

Exclusive enteral nutrition (EEN) therapy effectively induces remission in pediatric Crohn's disease (CD). However, this may depend on the type of enteral formula used. Moreover, data on the efficacy of amino acid-based EEN are limited. Thus, we aimed to prospectively evaluate the efficacy of amino acid-based formulas for EEN in pediatric patients with active CD.

Methods

Patients with active CD aged between 6 and 17 years were recruited into this prospective study from four hospitals in China between March 2019 and December 2021. Patients received EEN for 8 weeks. Inflammatory and nutrition-associated indices were evaluated at 0, 4, and 8 weeks after treatment. Paired t-tests and Wilcoxon signed-rank tests were used to compare continuous and categorical var

SUBMITTER: Yang Q 

PROVIDER: S-EPMC10746840 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature