Circulating Biomarkers for Monitoring Chemotherapy-Induced Cardiotoxicity in Children.

ABSTRACT: Most commonly diagnosed cancer pathologies in the pediatric population comprise leukemias and cancers of the nervous system. The percentage of cancer survivors increased from approximatively 50% to 80% thanks to improvements in medical treatments and the introduction of new chemotherapies. However, as a consequence, heart disease has become the main cause of death in the children due to the cardiotoxicity induced by chemotherapy treatments. The use of different cardiovascular biomarkers, complementing data obtained from electrocardiogram, echocardiography cardiac imaging, and evaluation of clinical symptoms, is considered a routine in clinical diagnosis, prognosis, risk stratification, and differential diagnosis. Cardiac troponin and natriuretic peptides are the best-validated biomarkers b

SUBMITTER: Meo L 

PROVIDER: S-EPMC10747387 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature