An Array SPRi Biosensor for the Determination of Follicle-Stimulating Hormone in Blood Plasma.

ABSTRACT: Follicle-stimulating hormone (FSH) regulates the development, growth, pubertal maturation and reproductive processes of the human body. The determination of serous FSH concentration is significant as an alternative to testicular biopsy in the case of boys suffering from cryptorchidism after orchidopexy, and as a means of determining the menopausal stage in women. The aim of this investigation is to develop a specific array surface plasmon resonance imaging (SPRi) biosensor for the determination of FSH in body liquids such as blood plasma, obtaining sufficient sensitivity to determine FSH at levels characteristic for that hormone in blood plasma, without any signal enhancement. The biosensor consists of a mouse monoclonal anti-FSH antibody attached to the gold surface of a chip via a cystea

SUBMITTER: Sankiewicz A 

PROVIDER: S-EPMC10747586 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature