Association between Parkinson's disease and the risk of adverse cardiovascular events: a systematic review and meta-analysis.

ABSTRACT:

Background

This review aims to examine the association of Parkinson's disease (PD) with the increased risk of cardiovascular events.

Methods

PubMed, Embase, CENTRAL, and Scopus databases were electronically searched for papers published up to 5 May 2023. Studies reporting the association between PD and the subsequent risks of stroke, myocardial infarction (MI), and cardiovascular mortality were included.

Results

Sixteen studies were included in this review. The clinical data of 101,712 PD patients were compared with that of the control group of 204,901 patients without PD in the included studies. Meta-analysis showed that PD patients had an increased risk of stroke compared with patients without PD (odds ratio (OR): 1.49; 95% confidence interval (CI): 1.30, 1.72; I

SUBMITTER: Hu Y 

PROVIDER: S-EPMC10748497 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature