Dataset Information

Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference.

ABSTRACT:

Background and objective

Reference values of physical activity to interpret longitudinal changes are not available in patients with idiopathic pulmonary fibrosis (IPF). This study aimed to define the minimal clinical important difference (MCID) of longitudinal changes in physical activity in patients with IPF.

Methods

Using accelerometry, physical activity (steps per day) was measured and compared at baseline and 6-months follow-up in patients with IPF. We calculated MCID of daily step count using multiple anchor-based and distribution-based methods. Forced vital capacity and 6-minute walk distance were applied as anchors in anchor-based methods. Effect size and standard error of measurement were used to calculate MCID in distribution-based methods.

Results

One-hundred and five patients were enrolled in the study (mean age: 68.5 ± 7.5 years). Step count significantly decreased from baseline to 6-months follow-up (-461 ± 2402, p = .031). MCID calculated by anchor-based and distribution-based methods ranged from 570-1358 steps.

Conclusion

Daily step count significantly declined over 6-months in patients with IPF. MCID calculated by multiple anchor-based and distribution-based methods was 570 to 1358 steps/day. These findings contribute to interpretation of the longitudinal changes of physical activity that will assist its use as a clinical and research outcome in patients with IPF.

SUBMITTER: Shingai K

PROVIDER: S-EPMC10748643 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature

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Publications

Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference.

Shingai Kazuya K Matsuda Toshiaki T Kondoh Yasuhiro Y Kimura Tomoki T Kataoka Kensuke K Yokoyama Toshiki T Yamano Yasuhiko Y Ogawa Tomoya T Watanabe Fumiko F Hirasawa Jun J Reid W Darlene WD Kozu Ryo R

Chronic respiratory disease 20230101

<h4>Background and objective</h4>Reference values of physical activity to interpret longitudinal changes are not available in patients with idiopathic pulmonary fibrosis (IPF). This study aimed to define the minimal clinical important difference (MCID) of longitudinal changes in physical activity in patients with IPF.<h4>Methods</h4>Using accelerometry, physical activity (steps per day) was measured and compared at baseline and 6-months follow-up in patients with IPF. We calculated MCID of daily ...[more]

PMID: 38108832

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Dataset Information

Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference.

Background and objective

Methods

Results

Conclusion

Publications

Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference.

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