Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference.

ABSTRACT:

Background and objective

Reference values of physical activity to interpret longitudinal changes are not available in patients with idiopathic pulmonary fibrosis (IPF). This study aimed to define the minimal clinical important difference (MCID) of longitudinal changes in physical activity in patients with IPF.

Methods

Using accelerometry, physical activity (steps per day) was measured and compared at baseline and 6-months follow-up in patients with IPF. We calculated MCID of daily step count using multiple anchor-based and distribution-based methods. Forced vital capacity and 6-minute walk distance were applied as anchors in anchor-based methods. Effect size and standard error of measurement were used to calculate MCID in distribution-based methods.

Results

One-hundre

SUBMITTER: Shingai K 

PROVIDER: S-EPMC10748643 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature