Application of deep learning in the diagnosis and evaluation of ulcerative colitis disease severity.

ABSTRACT:

Background

Achieving endoscopic and histological remission is a critical treatment objective in ulcerative colitis (UC). Nevertheless, interobserver variability can significantly impact overall assessment performance.

Objectives

We aimed to develop a deep learning algorithm for the real-time and objective evaluation of endoscopic disease activity and prediction of histological remission in UC.

Design

This is a retrospective diagnostic study.

Methods

Two convolutional neural network (CNN) models were constructed and trained using 12,257 endoscopic images and biopsy results sourced from 1124 UC patients who underwent colonoscopy at a single center from January 2018 to December 2022. Mayo Endoscopy Subscore (MES) and UC Endoscopic Index of Severity Score (UCEIS) a

SUBMITTER: Jiang X 

PROVIDER: S-EPMC10748675 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature