Changes in Serum Concentrations of Bone Turnover Markers in Healthy Pregnant Women.

ABSTRACT:

Background

Changes in bone metabolism during pregnancy have not received sufficient attention because of the lack of effective screening tools. Bone turnover markers (BTMs) could reflect the changes of bone metabolism. Currently, reference intervals for bone metabolism during normal pregnancy are inconclusive. This study aimed to determine reference intervals for BTMs in pregnant women taking prenatal care and to facilitate clinical research on diseases affecting bone metabolism during pregnancy.

Methods

We surveyed 120 low-risk pregnant women attending routine antenatal care from January 2020 to March 2020. The serum levels of procollagen type I N-propeptide (PINP), N-terminal osteocalcin (N-MID), and C-terminal telopeptide of type I collagen (β-CTX) were measured in

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC10748724 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature