Association between dementia risk and ulcerative colitis, with and without colectomy: a Swedish population-based register study.

ABSTRACT:

Objective

This study aims to investigate the association of ulcerative colitis (UC) with all-cause dementia and assess differences in those with and without a total colectomy.

Design, setting and participants

This Swedish prospective register-based study comprised 4.8 million individuals aged at least 59 years between 1964 and 2018 with the linkage of several Swedish national registers.

Primary and secondary outcome measures

Individuals with dementia were defined according to International Classification of Diseases diagnostic codes and Anatomical Therapeutic Classification codes for medication prescriptions. Fitting Cox hazards models, the risk of developing all-cause dementia in individuals with and without UC was estimated. Further, we compared the risk of all-caus

SUBMITTER: Garcia-Argibay M 

PROVIDER: S-EPMC10749019 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature