Factors associated with the response to postnatal dexamethasone use in very low birthweight infants: a nationwide cohort study.

ABSTRACT:

Background

Dexamethasone is widely used as a systemic corticosteroid to treat and prevent bronchopulmonary dysplasia (BPD) in preterm infants. We evaluated the current epidemiology of dexamethasone use to prevent BPD and analyse the factors associated with the response to dexamethasone in very low birthweight infants using a nationwide database.

Methods

We included very low birthweight infants born between January 2013 and December 2020 with a gestational age of 23-31 weeks using data from the Korean Neonatal Network registry. Patients were grouped based on their dexamethasone use into 'Dex' or 'No Dex' groups. Clinical variables and data were collected, and the annual trends of dexamethasone use and the proportion of patients who received dexamethasone according to gestatio

SUBMITTER: Baek SH 

PROVIDER: S-EPMC10749060 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature