Advancing Fifth Percentile Hazard Concentration Estimation Using Toxicity-Normalized Species Sensitivity Distributions.

ABSTRACT: The species sensitivity distribution (SSD) is an internationally accepted approach to hazard estimation using the probability distribution of toxicity values that is representative of the sensitivity of a group of species to a chemical. Application of SSDs in ecological risk assessment has been limited by insufficient taxonomic diversity of species to estimate a statistically robust fifth percentile hazard concentration (HC5). We used the toxicity-normalized SSD (SSDn) approach, (Lambert, F. N.; Raimondo, S.; Barron, M. G. Environ. Sci. Technol.2022,56, 8278-8289), modified to include all possible normalizing species, to estimate HC5 values for acute toxicity data for groups of carbamate and organophosphorous insecticides. We computed mean and variance of single chemic

SUBMITTER: Dhond AK 

PROVIDER: S-EPMC10749190 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature