Transcranial burst electrical stimulation contributes to neuromodulatory effects in the rat motor cortex.

ABSTRACT:

Background and objective

Transcranial Burst Electrical Stimulation (tBES) is an innovative non-invasive brain stimulation technique that combines direct current (DC) and theta burst stimulation (TBS) for brain neuromodulation. It has been suggested that the tBES protocol may efficiently induce neuroplasticity. However, few studies have systematically tested neuromodulatory effects and underlying neurophysiological mechanisms by manipulating the polarity of DC and TBS patterns. This study aimed to develop the platform and assess neuromodulatory effects and neuronal activity changes following tBES.

Methods

Five groups of rats were exposed to anodal DC combined with intermittent TBS (tBES+), cathodal DC combined with continuous TBS (tBES-), anodal and cathodal transcranial dire

SUBMITTER: Nguyen TXD 

PROVIDER: S-EPMC10749301 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature