Quantitative assessment of airway wall thickness in COPD patients with interstitial lung abnormalities.

ABSTRACT:

Background

Whether the airway is involved in the pathogenesis of interstitial lung abnormalities (ILA) is not well understood. Also the impact of ILA on lung function in COPD patients remains controversial. We aimed to assess the quantitative CT measurements of airway wall thickness (AWT) and lung function according to ILA status in COPD patients.

Methods

157 COPD patients discharged from our hospital from August 1, 2019 through August 31, 2022 who underwent chest CT imagings and pulmonary function tests were retrospectively enrolled. Linear regression analysis and multiple models were used to analyze associations between quantitative assessment of airway wall changes and the presence of ILA.

Results

In 157 COPD patients, 23 patients (14.6%) had equivocal ILA, 42 pati

SUBMITTER: Ji Y 

PROVIDER: S-EPMC10749311 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature